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Anonymous at Fri, 15 Mar 2024 23:29:13 UTC No. 16080188
Anyone here self-studied chemistry to a reasonably advanced level? I'm four years out of a math+compsci degree and still can't get any pussy, so I'm thinking of taking up chemistry in my spare time. If that's (you), what resources have you found best, and what have you learned to avoid?
Anonymous at Fri, 15 Mar 2024 23:36:59 UTC No. 16080201
you sure do seem to like talking about yourself on social media
Anonymous at Fri, 15 Mar 2024 23:40:33 UTC No. 16080206
>>16080188
Bumping for interest
Anonymous at Sat, 16 Mar 2024 00:53:24 UTC No. 16080309
>>16080201
Please go away
Anonymous at Sat, 16 Mar 2024 04:11:51 UTC No. 16080555
>>16080188
Read about medications on Wikipedia. Notice similar medications and their structures. Notice their biological targets. Start with superficial medchem; learn the basic accepted structure/activity relationship for a set of common medications or drug targets. Break it down into moiety: which parts of a molecule are essential for binding? Go further with ADME and learn the basics of membrane diffusion, LogP, metabolism (how can a molecule reasonably be modified in vivo for excretion), etc.
Cover all of those basic things and you've done a few things for yourself: you've become more familiar with an extremely small subset of well-studied compounds, understand concepts like solvent-accessible surfaces, the effects of physiological pH on active substances and their ADME, etc.
With this information, you can go into all kinds of chemistry. If you want to learn more about the enzymes that catalyze modifications for metabolism and the vast majority of drug targets, study biochemistry. If you want to learn more about the physical characteristics of compounds and devise means of synthesis while balancing molecular design fundamentals, study organic chemistry. I honestly know very little about inorganic chemistry and can't tell you about metal complexes for example, but if you wanted to learn more about crystal structure, complexes and other shit, inorganic is another way.
I studied this way prior to a biochemistry bs and was comfortable with concepts covered in ochem I/II and biochem. That's not to say I knew everything going in, but it was a real walk in the park whereas most people dreaded ochem. I loved it honestly. Probably my favorite couple of courses.
Anonymous at Sat, 16 Mar 2024 04:13:21 UTC No. 16080557
>>16080188
I guess to better answer your questions:
>what resources have you found best
Wikipedia, PubChem
>and what have you learned to avoid
Everything else
Anonymous at Sat, 16 Mar 2024 06:08:52 UTC No. 16080674
>>16080309
it's probably a bot or a schizo, neither of which responds to humans