๐งต /mnt/ - molecular nanotechnology general
Anonymous at Mon, 18 Mar 2024 01:36:43 UTC No. 16083930
SMOL edition
Discuss molecular nanotechnology research, companies, startups, implications. Anything to with molecular nanotechnology.
And please keep your discussion limited to molecular nanotechnology, not soiboy nu-nanotechnology.
Anonymous at Mon, 18 Mar 2024 01:40:10 UTC No. 16083939
prediction: nobody replies, but OP continues to vainly self bump "my thread" for days/weeks until it finally dies
Anonymous at Mon, 18 Mar 2024 01:46:00 UTC No. 16083951
>>16083939
Guess this topic is to high IQ for sci
Anonymous at Mon, 18 Mar 2024 02:04:14 UTC No. 16083990
bump
Anonymous at Mon, 18 Mar 2024 02:38:43 UTC No. 16084033
>>16084018
conspiracy, anon it's real
Anonymous at Mon, 18 Mar 2024 02:45:31 UTC No. 16084043
>>16084033
never said it wasn't
https://betakit.com/government-inve
https://patents.google.com/?assigne
Anonymous at Mon, 18 Mar 2024 03:18:48 UTC No. 16084098
There is a team at my company working on lipid nanoparticles for drug delivery. I have to order very expensive special lipids for them.
Anonymous at Mon, 18 Mar 2024 03:21:08 UTC No. 16084101
>>16084098
I also worked at the place who developed electronic ink. That definitely involved at least ink nanoparticles.
Anonymous at Mon, 18 Mar 2024 03:22:09 UTC No. 16084102
>>16083951
It's probably just niche
Anonymous at Mon, 18 Mar 2024 04:32:31 UTC No. 16084172
>>16083930
How many times has this thread been killed?
Anonymous at Mon, 18 Mar 2024 04:56:07 UTC No. 16084191
can i work in this field coming from medicine? (6 year degree in europe) maybe a masters somehow?
Anonymous at Mon, 18 Mar 2024 05:02:58 UTC No. 16084200
really shouldn't be feeding OP, but there have been some MNT developments recently. Can't post the actual link because it's in nature:
https://www.sciencedaily.com/releas
Title's: "Intelligent synthesis of magnetic nanographenes via chemist-intuited atomic robotic probe." AI's being used to controllably form covalent bonds between individual atoms to build stuff.
Anonymous at Mon, 18 Mar 2024 05:04:47 UTC No. 16084205
>>16084200
https://www.nature.com/articles/s44
Anonymous at Mon, 18 Mar 2024 05:10:01 UTC No. 16084213
>>16084200
more pics
>>16084205
I'll be damned, nature used to be banned from /sci/
>>16084172
I wouldn't be very helpful
Anonymous at Mon, 18 Mar 2024 05:18:36 UTC No. 16084225
hello sirs. is this the way to atomic 3d printer please?
Anonymous at Mon, 18 Mar 2024 05:22:56 UTC No. 16084227
>>16083930
Basic ATP Synthase bump
Anonymous at Mon, 18 Mar 2024 05:31:49 UTC No. 16084237
>>16084227
/sci/ is a slow board, you do not need to bump every minute
Anonymous at Mon, 18 Mar 2024 05:31:56 UTC No. 16084238
>>16084227
that gives me anxiety. so much shit happening in me that I have almost zero control of. at that scale.
Anonymous at Mon, 18 Mar 2024 06:05:26 UTC No. 16084274
>>16083930
have these things ever been used for anything ever?
and what's the synthesis of your pic like?
Anonymous at Mon, 18 Mar 2024 06:07:31 UTC No. 16084277
>>16084274
>>have these things ever been used for anything ever?
nope.
>>and what's the synthesis of your pic like?
no one has the faintest idea, but they ain't gonna be made in solution I can tell you that. Molecular rotors are a thing though. They can be used to measure viscosity inside cells.
Anonymous at Mon, 18 Mar 2024 06:09:05 UTC No. 16084279
>>16084277
intredasting
Anonymous at Mon, 18 Mar 2024 15:50:42 UTC No. 16084889
>>16084225
india no.1 superpower 2030.
Barkon at Mon, 18 Mar 2024 15:51:19 UTC No. 16084892
>>16084889
Homo dribble. Do the working out first before posting fags lol
Kys now
Anonymous at Tue, 19 Mar 2024 02:02:46 UTC No. 16085852
>>16084213
it was never banned, you were just too low iq to figure out how to circumvent the regular expression that prevents posting phone numbers
Anonymous at Tue, 19 Mar 2024 02:18:42 UTC No. 16085872
>>16084892
chill bro
Pax at Tue, 19 Mar 2024 09:50:03 UTC No. 16086235
We are on the job ascertaining the pharmacokinetics of this compound and considering it alongside other options such as (DHA-)curcumin and mimosine-capped gold nanoparticles for the chelation of iron in neural tissue and their lysosomes from ferritin, hepcidin, and the labile iron pool and usage alongside intranasal erythropoietin.
As you may know there is a risk of mucormycosis with deferoxamine which can be attenuated with safe antifungals like intranasal rapamycin (I took 150mg over the course of a day) or NAC. This risk is due to the siderophore structure of deferoxamine and the resultant iron chelate, ferrioxamine B, giving life to this strain of fungus, while healthy people are normally immune to it.
However, the large molecular structure gives deferoxamine a low membrane permeability whereby it can only enter the cell via endocytosis instead of passive diffusion. This favors chelation of ferritin via endolysosomal degradation upon entering the lysosomal lumen. Whereas more permeable, small molecules like desferasirox and deferiprone induce ferritin degradation via the proteasome.
>Specific iron chelators determine the route of ferritin degradation: https://www.ncbi.nlm.nih.gov/pmc/ar
We leave it as an exercise to the reader to find out which side of the coin of autophagy is more important for ferritin: lysosomal, or ubiquitin-proteasomal.
https://www.youtube.com/watch?v=adr
Pax at Tue, 19 Mar 2024 09:52:07 UTC No. 16086237
>>16086235
we can apply the understanding gained from study of intranasal deferoxamine towards other interventions such as the use of DHA-curcumin microemulsions(its fairly easy to make these with a vacuum blender and some stabilizing agents) Curcumin has potent iron chelation properties and DHA microemulsions promote >66 fold increased levels within the brain than from oral use. This is quite significant as possibly anyone that put in the effort to understand how to make DHA microemulsions can formulate them at home.
https://pubmed.ncbi.nlm.nih.gov/281
There's also a amino acid called mimosine with iron chelating properties and researchers have made mimosine capped gold nanoparticles by conjugating mimosine to gold. This can be applied intranasally and is shown in mouse models to mitigate amyloid beta induced cognitive dysfunction and is shown to be non toxic in every concentration tested in this mouse model. That would not be impossible for someone with a bachelors understanding of chemistry to produce with the right equipment.
https://www.sciencedirect.com/scien
intranasal wheatgrass juice would introduce high ammounts of chlorophyll into the brain to support metabolism of our mitochondria. Chlorophyll can be taken up by our cell lines especially our neurons and can contribute to ATP production.
https://pubmed.ncbi.nlm.nih.gov/241
This would greatly potentiate the efficacy of Laser photobiomodulation in the brain, and could be easily applied with use of commercially available photobiomodulation devices like those produced by vielight.
Anonymous at Tue, 19 Mar 2024 10:00:51 UTC No. 16086253
>>16084227
It's fascinating to think all of that stuff has to be re-created every time a cell divides.
Anonymous at Tue, 19 Mar 2024 16:10:09 UTC No. 16086663
>>16085825
love these lil niggas like you wouldn't believe
Anonymous at Wed, 20 Mar 2024 04:57:30 UTC No. 16087595
>>16086253
It's even fascinatinger to think that all of this is just randomly created by a random soup of amino acids getting struck by lightning
Anonymous at Wed, 20 Mar 2024 05:00:18 UTC No. 16087596
>>16087595
that wasn't created by a lightning anon. some very early form of something simple 4 billion years ago.
that's like saying you discovered CPUs when you first time grabbed a rock as a monkey. you kinda didn't, shit built on itself for a long ass time.
Anonymous at Wed, 20 Mar 2024 14:15:19 UTC No. 16088103
chemistry is done. there is nothing new to make
Anonymous at Wed, 20 Mar 2024 14:55:48 UTC No. 16088145
>>16088103
we need a guy like this again