🧵 9-me-bc for cognitive enhancement
Anonymous at Sun, 24 Mar 2024 07:21:22 UTC No. 16093827
has anyone taken/experimented with this?
I am using it at the moment, on day 3. apparently, it upregulates tyrosine hydroxylase in the brain and increases dopamine receptors, as well as contributing to hippocampal neurogenesis through expression of various factors e.g. BDNF/NGF by astrocytes
it tastes fucking horrid though, and robs you of taste for at least 24 hours. I dose once daily, so I'm planning on being a total ascetic for the next 15-20 days when it comes to food
Anonymous at Sun, 24 Mar 2024 08:08:41 UTC No. 16093871
>>16093827
Not exactly this, but have you heard of noopept?
Anonymous at Sun, 24 Mar 2024 08:10:10 UTC No. 16093872
>>16093827
have you tried jenkum?
Anonymous at Sun, 24 Mar 2024 09:43:24 UTC No. 16093957
>>16093871
nope
>>16093872
nope
tell me more about it
Anonymous at Sun, 24 Mar 2024 10:30:52 UTC No. 16094003
>>16093957
Noopept probably increases BDNF...
It's dirt cheap, and synonymous of nootropic.
Anonymous at Sun, 24 Mar 2024 14:20:09 UTC No. 16094269
>>16093827
9mebc is pretty good, it has similar effect to dopamine detox. I used to take it and still have some in the drawer. After about a week you start feeling more energized, more motivated, in better mood and even get inspired to do great things. I usually take it for around 10 days because I don't think there's more benefit beyond that. It won't make you smarter though.
There's another drug called Agomelatine, that works similarly, but works overnight. It's antidepressant, it's agonist of melatonin receptors and antagonist of serotonin receptors. This somehow increases dopamine in the brain the next day. You take it before sleep and next morning wake up full of energy and ready to slay. I take 12.5mg(half a pill) before sleep, because 25mg gives me little bit of nausea and dizziness. 12.5mg works quite fine. Don't take it everyday, because it has side effects on liver, kidney and weight gain. Take it before important days when you need get a lot of challenging things done.
Another way to increase dopamine is to take Bromantane and L-Tyrosine. This combo acutely increases dopamine and puts you in really good mood. Might get even euphoric if you overdo it.
And the last but not least is Modafinil. I don't feel much on it, but 50mg get's everything done. I used to take it when I needed to study Organic Chemistry.
None of the above makes you smarter. If you want to get smarter, improve memory, recall and creativity, thy this combo: Alpha GPC + Donepezil + Choline. This is the only stack in my experience that noticeably makes it easier to study. Don't stack it with Bromantane or Modafinil, because it might give you anxiety.
Anonymous at Sun, 24 Mar 2024 20:38:06 UTC No. 16094802
>>16094003
interesting
I'm only interested in long-lasting solutions
this one seems to be the only one that stood out to me in terms of that
>>16094206
yes, positive changes in mood, new perspectives/thinking which makes me consider neuroplasticity since ketamine has that effect on me too, and I feel more motivated
all of this could be placebo though, it's day 3 of my trial
>>16094269
interesting, why don't you take it consistently for longer?
good combos there
I find 2-fma is the cleanest stim for productivity, though very poorly researched as well
from the way it feels, it's probably less neurotoxic than amphetamine from my perspective
Anonymous at Sun, 24 Mar 2024 22:00:59 UTC No. 16094934
>>16094269
>Alpha GPC
Is it worth adding Huperzine A if you take Alpha GPC? Also, redpill me on methylene blue.
Anonymous at Sun, 24 Mar 2024 22:06:10 UTC No. 16094948
>>16094934
Donepezil works in a similar way to Huperzine A, but much cleaner and more potent. I see no reason to pick Huperzine A over Donepezil. Never used Methylene Blue, so can't speak on that.
Anonymous at Sun, 24 Mar 2024 22:57:28 UTC No. 16095056
>>16094269
>Bromantane
Does that not fuck your dop receptors? Id imagine there's some tradeoff when you're overloading your usual dopamine pathways. Messing up with neurotransmitters always scares me
Anonymous at Mon, 25 Mar 2024 02:56:28 UTC No. 16095335
>>16095056
>Does that not fuck your dop receptors?
Not really. I've never noticed a significant crash from Bromantane. Maybe because it has long lasting effect, I usually continued to feel it for 2-3 days. Also never really abused it. I used only 50mg and only on days when I felt I really needed it. I had bad experience with adderall in my teens. I abused it for several years, got addicted and I quit cold turkey after I finished high school and got accepted to college, I had severe depression. Everything, I mean slightest activities like doing my bed or brushing my teeth felt like a insurmountable task. Going out and playing soccer with friends... forget about it. Not gonna happen. Funny enough, I just stayed in my bed and did nothing and it cured my depression in a month or so. I didn't watch movies and didn't use social media, because I felt guilty. So I just laid on my bed and read books all day, everyday and it accidentally dopamine detox my brain. Because of that experience I was very careful with drugs during my college years. I used low doses, never for a prolonged period of time and always cycled between several compounds. It all worked quite well too, I cruised through college with close to perfect grades.
>>16094802
>interesting, why don't you take it consistently for longer?
I figured it did its job to re-sensitizeby receptors, so why push it?
Anonymous at Mon, 25 Mar 2024 05:00:18 UTC No. 16095439
>>16095335
did you take 9-me-bc sublingually?
Anonymous at Mon, 25 Mar 2024 05:48:18 UTC No. 16095464
>>16093872
>>16093957
Seconding this OP should definitely give jenkem a try
Anonymous at Mon, 25 Mar 2024 06:52:38 UTC No. 16095519
>>16095439
Yeah, 10mg sublingually. Tastes not great and numbs your tongue. It's tolerable if you prepare yourself to it mentally. I've taken it orally and didn't feel anything, no choice, sublingual is the way to go.
Anonymous at Mon, 25 Mar 2024 10:43:45 UTC No. 16095712
>>16095519
i'm taking 50-75mg sublingually. safe?>>16095519
Anonymous at Mon, 25 Mar 2024 10:50:11 UTC No. 16095721
>>16095712
I don't know, but dude, why take that much? It's supposedly makes your skin more sensitive to sun, so be careful with that. But damn, can you even feel food after taking that much?
Anonymous at Mon, 25 Mar 2024 16:39:09 UTC No. 16096194
>>16095721
idk, if i'm using this at all then i should go all out
yes losing taste is fucked, thats the worst
if im losing taste might as well dose higher for shorter period than go prolonged