🗑️ 🧵 How is your day/night going /sci/entists?
Anonymous at Sat, 15 Jun 2024 23:15:58 UTC No. 16237001
> Flatmate got drunk and is yapping about RNA world hypothesis
> Have to blast max volume Burzum on headphones to not hear the puke inducing popsci babble
Anonymous at Sun, 16 Jun 2024 13:46:59 UTC No. 16237775
>>16237694
after I finished a chapter of my thesis, and he stopped yapping about RNA I started drinking with them and ended staying up all night
Anonymous at Sun, 16 Jun 2024 14:35:06 UTC No. 16237829
>>16237775
>chapter
How much left to write, Anon?
Anonymous at Sun, 16 Jun 2024 15:52:39 UTC No. 16237912
>>16237829
I don't know. My advisor told me 5 pages of introduction/literature review should be enough, and to include some figures. Reviewing, writting and preparing figures took me a week. Don't know if I'm lagging behind or doing good. I could potentially describe all known pathways of mitochondrial protein import, rather than an abstract "general" case. That could bloat the intro by 30% or 50%, but does not seem relevant enough when my experiments centered around substituting one receptor subunit of one import complex. I also took half a page to explain the naming conventions, because they are a bit convoluted, and established shorthand notation of genotypes for easier reading. Which seems partially like filler text, altough I wrote it believing someone who never worked on mitochondrial protein import could get overwhelmed. Method and results are just writting up what I did, which is halfway done, and should go faster as I'm only repeating what I did, without the need to extract information from a total of 600 pages of papers. Especially when those idiots keep repeating, "X is the major component", "Y is the main entry" without quantitative proof. I always intended to keep my thesis within 30 pages, excluding the bibliography and titlepage, but finding the golden mean between rough outlines and enumerating all known information is hard, especially reading things like these about the process of writing your thesis
> The last two Diplomarbeit "theses" (Masters in Biochemistry) I have supervised have been 100-110 pages including roughly 40 figures, 20 tables and around 150 references.
> I give the students 8 months for the laboratory experiments and 4 weeks to write and defend the document in public. A lot of pressure on the students, but good preparation for their future.
Anonymous at Sun, 16 Jun 2024 16:15:55 UTC No. 16237944
>>16237912
>Reviewing, writting and preparing figures took me a week.
A week sounds normal.
> I also took half a page to explain the naming conventions, because they are a bit convoluted, and established shorthand notation of genotypes for easier reading. Which seems partially like filler text, altough I wrote it believing someone who never worked on mitochondrial protein import could get overwhelmed.
Couldn't hurt.
>I always intended to keep my thesis within 30 pages, excluding the bibliography and titlepage, but finding the golden mean between rough outlines and enumerating all known information is hard, especially reading things like these about the process of writing your thesis
As long as the committee passes you. :)
Anonymous at Sun, 16 Jun 2024 16:36:43 UTC No. 16237972
>>16237001
>Have to blast max volume Burzum
Metal manchildren are the vegan soibois of music. They literally can't breathe for a few seconds without letting everyone know about their preferences in "music".
Anonymous at Mon, 17 Jun 2024 01:54:39 UTC No. 16238774
>>16237972
>not listening to s;g most on repeat for 10 hours
It's like he's not a real scientists.
Anonymous at Mon, 17 Jun 2024 01:55:49 UTC No. 16238777
>>16238774
>not listening to 2hu remixes 24/7
You're not a mathematician. Sorry.
Anonymous at Mon, 17 Jun 2024 14:26:43 UTC No. 16239469
>>16237912
>Especially when those idiots keep repeating, "X is the major component", "Y is the main entry" without quantitative proof.
Not even a citation?
Anonymous at Mon, 17 Jun 2024 20:37:31 UTC No. 16239940
>>16239469
> "the yeast translocase of the outer membrane (TOM) complex, which mediates the entry of most mitochondrial proteins into the mitochondrial interior."
no citation, in a review article published in 16.6 IF journal (annual review of biochemistry)
> "Nearly all mitochondrial preproteins are imported via the gen- eral entry gate, the translocase of the outer membrane or TOM complex (Figure 1B)"
no citation, published in The Cell
> "The primary entry point for nuclear-encoded preproteins into mitochondria is the
translocase of the outer membrane (TOM) complex."
no citation, published in The Cells (kek), ~6 IF
I found one paper about MIM complex, and indeed some proteins don't go throught TOM pore, but sometimes some components of TOM complex moonlight and take part in non-TOM OMM transmembrane protein import. I don't know how those guys can make such statements, when in the last 10 years the known mitochondrial of yeast grew from 700 to 1200 proteins, and curiously the major component is the most understood one.
also, in reviews of the history of mitochondria research, some authors cited the first "confirmed" mitochondria description, as some 19th century german book, as if I could confirm this claim.
Anonymous at Tue, 18 Jun 2024 02:18:52 UTC No. 16240404
>>16240364
nigga, my paper is overdue by 2 years, get on my level
Anonymous at Tue, 18 Jun 2024 02:33:13 UTC No. 16240421
>>16240364
>>16240404
>tfw I have ascended to a level beyond plebeian feats of intellect and no longer have to write "papers"
It is the best feeling in the world to know you no longer have to seek the approval of your betters, because you are now the better one.
Anonymous at Tue, 18 Jun 2024 02:43:31 UTC No. 16240435
>>16237001
I'm on my third week of delaying my current task of centering a div and changing some labels. I make 130k a year.
Anonymous at Tue, 18 Jun 2024 03:22:26 UTC No. 16240478
>>16240421
>It is the best feeling in the world to know you no longer have to seek the approval of your betters, because you are now the better one.
You're only better if you aren't stuck making students write papers.