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๐Ÿงต Terminal/Paradoxical Lucidity

Anonymous No. 16433562

Why do some Alzheimer's patients regain nearly full cognition, and memory just prior to their death? If they lost the abilities, and it was due to neuronal death, then how do they regain the abilities without regaining the neurons? Why does it occur just before death? Is it God giving one last act of mercy before the end, for both the patient and their loved ones?

Anonymous No. 16433597

Suggests that memories are more inaccessible than outright lost. The brain is pretty flexible in dealing with injury, plenty of people lose large portions of it and retain normal function. Not unlikely that shifting pathways could temporarily "unlock" previously out of reach memories for a short time before losing them again.
The observation that it usually happens shortly before death is probably just a consequence of the fact that that's when family members are most likely to be around to notice, everyone will know when grandma remembers their names on her deathbed but no one will have seen the same thing happening when she was alone at the nursing home 2 months ago.

Anonymous No. 16434107

>>16433562
isnt this more common with dementia patients?

ask your local doctor.

Anonymous No. 16434352

>>16433562
A lot of memory engrams don't necessarily decay, but can be dysfunctional or inaccessible.
Imagine consciousness like a hologram and the brain as its boot media.
Now, we do actually see the same kind of terminal lucidity, as well as a surge of energy in patients without neurodegenerative disease.
So my guess is that the body mobilizes all of its remaining energy and nutrient stores in the hours preceding death.
Probably as one last-ditch effort in warding it off, possibly evolved to increase survival chances for infectious disease and such.
These resources then could affect cognition and general well-being.
I encourage you to look into some of the recent studies on the topic of ketones and ketosis in TBI and neurodegenerative disease. It seems to act as an alternative fuel, and that together with an immune response and some other components, such as changes in TNF presence may very well explain how patients with AD can regain their full memory before they die.

Anonymous No. 16434362

>>16434352
TNF should actually play a pretty big role in it. Hence, why perispinal etanercept works in TBI and stroke.
https://doi.org/10.1007/s40263-014-0174-2
https://doi.org/10.1080/13543784.2020.1709822
https://doi.org/10.7759/cureus.36185
https://doi.org/10.1586/ern.10.52

Anonymous No. 16434378

>>16433597
This is nonsense.
It is often the very observation of terminal lucidity by staff that alerts friends and family to come and say their goodbyes.
I encourage you to read these:
https://www.msn.com/en-us/health/medical/hospice-nurse-reveals-the-three-different-smells-that-lets-her-know-someone-is-dying/ar-BB1qqxVf
https://www.msn.com/en-us/health/medical/the-body-knows-when-death-is-near-and-it-begins-in-your-nose/ar-AA1n5wQz

Anonymous No. 16434403

>>16433562
>and it was due to neuronal death
Its typically due to neuronal inhibition certain proteins or bodies interfering with normal activity.
>Why does it occur just before death?
Because spontaneous lucidity episodes happen spontaneously, it is pretty common, but usually brief even just before death, some kind of stress or hormone may be involved, but its not just a terminal phenomenon.

https://pubmed.ncbi.nlm.nih.gov/38134428/
>Most caregivers reported at least 1 episode of lucidity.
>Episodes of lucidity were common, a finding seen in other studies.

Anonymous No. 16435646

>>16433562
It's DMT

Anonymous No. 16435725

circlejerk
addiction
bdsmh
neets
timelines
capital tickles. a pound of feathers is still ten times a decimal. cant stock washing the television. before tickling dying loved ones to make them smile cite your sources. :D

today, i didn't stick my hand up my ass and hole it up around the corner, authoritatively of course.