Anonymous at Mon, 17 Mar 2025 20:31:54 UTC No. 16621885

>>16621881
>epigenetic reprogramming
Which kind? It's a whole network of feedback systems that we don't fully understand, all of which contribute to age.

TDG !!HFjm3zKJ8pT at Mon, 17 Mar 2025 20:34:38 UTC No. 16621890

>>16621881

To repeat myself: insufficient. Tissue niches must be cleaned out first. Senescent cells and low level chronic inflammation would prevent any effective regeneration. Btw nice to have that old pic back again.

Anonymous at Tue, 18 Mar 2025 08:11:28 UTC No. 16622293

>>16621881
No, because that's not what causes aging.

Anonymous at Tue, 18 Mar 2025 08:18:58 UTC No. 16622294

>>16621881
>cure aging
Aging isn't a disease you dumb zoomer.

Anonymous at Tue, 18 Mar 2025 08:27:27 UTC No. 16622300

>>16622294
Not only is it a disease, it's immoral.

Anonymous at Tue, 18 Mar 2025 08:35:38 UTC No. 16622302

>>16621881
Ageing is literally solved already with present day tech.

Anonymous at Tue, 18 Mar 2025 09:16:38 UTC No. 16622309

>>16621881
Not really. Our bodies don't even have the capacity for decent cartilage regeneration, for example. Genes or not, there's barely any vessels supplying blood and lymph to them. You could extend your life all you want, it's not gonna be very fun without working joints.

Anonymous at Tue, 18 Mar 2025 11:34:07 UTC No. 16622343

>>16621890
And clearing senescent cells itself hinders regeneration and lowers mice lifespan. It’s the wrong approach.

Anonymous at Tue, 18 Mar 2025 12:05:03 UTC No. 16622349

>>16622343
You have to be careful because there’s some real wackos in this space trying to sell you supplements or research, where it is quasi anti-aging or quasi regenerative and there is no proof of life extension.

Regeneration is not longevity.
Cellular reprogramming may or may not be longevity.
Senolytics so far does no seem to be.
Calorie restriction and similar paths appears to be anti-aging.
Antivirals and antibiotics need to be explored for longevity.
So far there is a lot of great stuff being done but there is nothing I’d recommend other than what is already known about diet and diseases.

TDG !!HFjm3zKJ8pT at Tue, 18 Mar 2025 18:49:07 UTC No. 16622560

>>16622343

It is not as long as there are still regenerative elements active enough in the tissue niche. If not that needs to be stimulated. You will want a turnover hand in hand with repair of the messed up intracellular matrix ofc. No wonder it does damage in mice btw with their rapid lifestyle and aging ... likely the remaining regenerative reservoirs cannot keep up. Further, it might simply mess with immune cell differentiation if applied on the entire organism with the wrong timing. Senescence and senescence-like pathways still got some important functions aside from the shoddy tissue maintenance they usually cause.

Anonymous at Tue, 18 Mar 2025 18:58:43 UTC No. 16622565

>>16621881
yneos, also nyoes

Anonymous at Tue, 18 Mar 2025 20:31:02 UTC No. 16622643

>>16622309
Anything that was grown can be regrown

Anonymous at Thu, 20 Mar 2025 22:46:25 UTC No. 16624567

Bump

Anonymous at Thu, 20 Mar 2025 23:47:24 UTC No. 16624613

>>16621881
Currently humans do not know how to safely reprogram epigenome.
But humans know how to safely edit the genome, and that can and probably already does cure aging.
https://www.youtube.com/watch?v=87OUb8TBwX0
Here she speaks about it ten years ago, when it was first tried in humans (herself) openly. It was tried secretly on other guys maybe twenty years ago, because we know about this technology for more than twenty years now.

Anonymous at Sat, 22 Mar 2025 07:12:00 UTC No. 16625651

Humans would be better on focusing how to emulate the rainbow body phenomenon instead.