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🧵 What is the polar opposite of an orgasm?

Anonymous No. 16632633

During orgasms you release things like dopamine and endorphines etc, but what I'm wondering is a) What exact hormones are released, b) What are the exact opposites of said hormones, and c) is there a naturally occurring occasion where all of the opposite hormones are released at once.

Anonymous No. 16632660

>>16632633
During orgasms, the body releases a mix of neurotransmitters and hormones, including:
Dopamine: Associated with pleasure and reward.
Endorphins: Natural painkillers that induce euphoria.
Oxytocin: Promotes bonding and social connection (often called the "love hormone").
Serotonin: Contributes to mood stabilization and feelings of well-being.
Prolactin: Induces relaxation and post-orgasm satiety (linked to the refractory period).
Norepinephrine/Adrenaline: Increases heart rate and arousal (part of the sympathetic nervous system response).

The concept of "opposite" hormones is nuanced, as hormones interact in complex ways. However, based on antagonistic effects:
Dopamine Cortisol: Cortisol (a stress hormone) counteracts dopamine’s pleasure/reward effects.
Endorphins Substance P: Substance P transmits pain signals, opposing endorphins' pain-relieving role.
Oxytocin Adrenaline/Cortisol: Stress hormones like adrenaline/cortisol reduce social bonding and induce fight-or-flight responses.
Prolactin Dopamine: Dopamine inhibits prolactin release, promoting arousal (prolactin suppresses it post-orgasm).
Serotonin CRH (Corticotropin-Releasing Hormone): CRH drives stress responses, contrasting serotonin’s mood-stabilizing effects.

While stressful events naturally co-release several hormones that counteract the effects of orgasm-related chemicals, the idea of "exact opposites" is more functional than direct. The body’s stress response system broadly opposes the neurochemical state of orgasm, but not all antagonists are released at once in a single natural event. Adrenaline is also part of the sympathetic nervous system, which is active during both stress and sexual arousal.

deepseek r1

Anonymous No. 16632850

>>16632633
Not everything has opposites, but I'd imagine being in Zen state?

Anonymous No. 16632900

>>16632633
A panic attack maybe

Anonymous No. 16633278

>>16632633
Going through severe alcohol withdrawal or more specifically, delirium tremens.

Anonymous No. 16633297

>>16632660
So super shame? I felt that before, honestly would not wish it onto anyone else.

Anonymous No. 16633696

>>16632633
Id say fight or flight response

Anonymous No. 16634037

>>16632633
Anhedonia
its the inability to feel pleasure or joy
On anhedonia you dont eat as food doesnt feel good

Anonymous No. 16634042

The opposite is actually the lack of those hormones. So dopamine or endorphin downregulation. Any high dopamine activity causes a deficit of dopamine after.
Aka feeling bad after the dopamine wears off.